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Licenses come in three layers, and the layer determines who applies and when.

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Clinician licenses (the person)

State professional license in every state where patients are located (telehealth rule). DEA registration for prescribers (federal, per state where you practice), plus a state controlled-substance registration in the states that require their own. Specialty boards aren’t licenses but payers check them (CAQH).

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Entity registrations (the company)

Formation with the Secretary of State, EIN, state tax accounts (income or franchise, sales tax if you sell products, unemployment insurance), workers’ comp policy, and any state professional-entity registration (some medical and dental boards register the PC itself).

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Site permits (the location)

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Sequence and upkeep

Clinician licenses first (they gate credentialing), entity registrations at formation, site permits during the buildout month (the 4-month plan slots them). Then put every expiry date on the compliance calendar: DEA every 3 years, CLIA every 2, X-ray and business licenses annually in most states. A lapsed license is a billing stop, not a paperwork problem.